2025

Our Co-Founder in Conversation with XEIA Ventures

Tech

Ben joins Brom Rector on Human 3 to discuss:

0:00 - Intro  

1:38 - What does BCI (brain-computer interface) actually mean?

3:55 - The deadly brain cancer that Coherence is treating

8:01 - How can you treat cancer with electricity?

9:54 - Coherence’s billion dollar comp

12:52 - How does the Coherence device actually work?

19:00 - How MRI makes brain computer interface development difficult  

20:30 - Ben’s startup journey

21:30 - How implants are more convenient than drugs  

24:55 - Is neurotech getting overhyped?

28:04 - Are the obvious ideas taken?

29:00 - What will enable the next generation of BCIs?

30:30 -  What is the best dimension along which to analyze BCIs?

33:36 - Will people have multiple BCIs simultaneously?

35:45 - Is it easier to get a device  approved by the FDA than a drug?

40:15 - When is Coherence’s first trial?

42:00 - It’s capital allocators all the way down (clip)

44:20 - Advice for PhD students considering starting a company

The body runs on a bioelectronic

The body runs on a bioelectronic


Bioelectronic therapy at the cutting edge

Bioelectronic devices — tiny implants, smart wearables, and AI-powered neural systems — are a new interface between the human body and therapeutic technology.

The cutting edge of medicine is not only digital; it’s electric.


The body electric

Our bodies communicate both through chemicals like hormones and neurotransmitters and through electricity.

Tiny pulses of energy travel through nerves and tissues, orchestrating everything from your heartbeat to your thoughts. Neurons fire electrochemical impulses. The brain and nervous system function as complex, living circuits.

Every sensation, movement, and emotion begins as an electrical signal.

This electrical activity forms the bioelectronic code — a language of patterns, frequencies, and pulses that governs how we function, feel, and heal.

Health and disease are not just chemical or genetic. They are also electrical.

When signals misfire or communication breaks down, illness can follow — from chronic pain and depression to autoimmune disorders, paralysis, and aggressive cancers like glioblastoma.

Cancer rewritten

Cancer isn’t just a genetic anomaly. It’s an active participant in the body’s electrical system.

Cancer monitors the body’s bioelectronic signals and responds with its own, hijacking the neural pathways used for healing and immune coordination to fuel its own growth.

At Coherence, we’re overwriting cancer’s bioelectronic signals.

Particles image

The fourth pillar of cancer therapy

Cancer therapy has three pillars: drugs, radiotherapy, and surgery. We’re introducing a fourth pillar: electricity, via bioelectronic therapy. Bioelectronic therapy is divided into three primary modalities.


A new era in disease management

Coherence products read the body’s electrical signals and deliver precise electrical modulation to areas affected by disease. This rebalances tissue function, relieves symptoms, supercharges immune response, and slows disease progression.

By bringing bioelectronic systems into stasis, we extend and improve quality of life.


Unlike chemotherapy or other systemic drugs, targeted bioelectronic therapy contends with disease at its source. Electrically modulating aberrant bioelectrical signals offers a precise approach to treating disease while substantially minimizing side effects compared to conventional cancer treatment.

Targeted bioelectronic therapy shows promise across many conditions:




  • Restoring movement after paralysis through spinal or brain stimulation
  • Reversing stroke damage by reactivating dormant neural pathways
  • Treating depression or PTSD by rebalancing malfunctioning brain circuits
  • Boosting immunity or suppressing cancer by modulating nerve-to-immune signals

The Coherence platform

Our approach is built on three interconnected pillars:

Neurotechnology

We design implantable electronics capable of sensing and stimulating with unmatched precision.



They’re small enough to fit on your fingertip, yet powerful enough to influence how the body behaves.

Neurobiology

We are mapping how cancer communicates with the nervous system and learning how to intervene.



In collaboration with partners at Cambridge, Monash, and Stanford, we’re pioneering the new field of electro-oncology.

AI & machine learning

Our closed-loop systems continuously learn from each patient.
We use advanced AI to decode high-resolution electrical signals and identify the unique fingerprint of each disease. These insights fuel personalized therapies that adapt in real time and provide clinicians with a new tool to understand and personalise treatment.

As we scale, we’re building the largest dataset of disease evolution and brain state in history, unlocking unprecedented insights into the brain and body.


Glioma management

SOMA-1 is our flagship device: a minimally invasive, MRI-safe brain–computer interface implanted during existing neurosurgery. SOMA-1 both monitors and treats brain disorders like gliomas in real time.

  • Closed-loop stimulation reduces disease burden as it evolves.
  • Continuous recording tracks tumor behavior without repeated scans.
  • Adaptive AI personalizes therapy based on live data from the tumor environment.



SOMA-1 is therapy, diagnostics, and a living model — all in a device the size of a shirt button.

A patient-first paradigm

Gone are the days of burdensome treatments — no more head shaving, messy gel applications, bulky headgear that overheats, or cumbersome equipment.

With Coherence, patients can maintain their appearances and focus on enjoying life. 



Patients are augmented by a holistic therapeutic system — a button-sized therapeutic implant; a modern, minimalist wearable that sits comfortably on top of the ear; and a user-friendly app. 

This system greatly enhances quality of life — allowing patients to live easier, healthier, longer, and more joyful lives.

Bioelectronic cancer management

By decoding the body's electrical language, we’re unlocking a new way to understand and treat disease.

  • Smarter: Personalized, real-time therapy for each patient.
  • Faster: Deployable across conditions without years of redevelopment.
  • Deeper: Reaching the core bioelectrical mechanisms of disease.


Coherence is laying the foundation of electro-oncology.
Welcome to a new paradigm in medicine.




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The body runs on a bioelectronic

The body runs on a bioelectronic


Bioelectronic therapy at the cutting edge

Bioelectronic devices — tiny implants, smart wearables, and AI-powered neural systems — are a new interface between the human body and therapeutic technology.

The cutting edge of medicine is not only digital; it’s electric.


The body electric

Our bodies communicate both through chemicals like hormones and neurotransmitters and through electricity.

Tiny pulses of energy travel through nerves and tissues, orchestrating everything from your heartbeat to your thoughts. Neurons fire electrochemical impulses. The brain and nervous system function as complex, living circuits.

Every sensation, movement, and emotion begins as an electrical signal.

This electrical activity forms the bioelectronic code — a language of patterns, frequencies, and pulses that governs how we function, feel, and heal.

Health and disease are not just chemical or genetic. They are also electrical.

When signals misfire or communication breaks down, illness can follow — from chronic pain and depression to autoimmune disorders, paralysis, and aggressive cancers like glioblastoma.

Cancer rewritten

Cancer isn’t just a genetic anomaly. It’s an active participant in the body’s electrical system.

Cancer monitors the body’s bioelectronic signals and responds with its own, hijacking the neural pathways used for healing and immune coordination to fuel its own growth.

At Coherence, we’re overwriting cancer’s bioelectronic signals.

Particles image

The fourth pillar of cancer therapy

Cancer therapy has three pillars: drugs, radiotherapy, and surgery. We’re introducing a fourth pillar: electricity, via bioelectronic therapy. Bioelectronic therapy is divided into three primary modalities.


A new era in disease management

Coherence products read the body’s electrical signals and deliver precise electrical modulation to areas affected by disease. This rebalances tissue function, relieves symptoms, supercharges immune response, and slows disease progression.

By bringing bioelectronic systems into stasis, we extend and improve quality of life.


Unlike chemotherapy or other systemic drugs, targeted bioelectronic therapy contends with disease at its source. Electrically modulating aberrant bioelectrical signals offers a precise approach to treating disease while substantially minimizing side effects compared to conventional cancer treatment.

Targeted bioelectronic therapy shows promise across many conditions:




  • Restoring movement after paralysis through spinal or brain stimulation
  • Reversing stroke damage by reactivating dormant neural pathways
  • Treating depression or PTSD by rebalancing malfunctioning brain circuits
  • Boosting immunity or suppressing cancer by modulating nerve-to-immune signals

The Coherence platform

Our approach is built on three interconnected pillars:

Neurotechnology

We design implantable electronics capable of sensing and stimulating with unmatched precision.



They’re small enough to fit on your fingertip, yet powerful enough to influence how the body behaves.

Neurobiology

We are mapping how cancer communicates with the nervous system and learning how to intervene.



In collaboration with partners at Cambridge, Monash, and Stanford, we’re pioneering the new field of electro-oncology.

AI & machine learning

Our closed-loop systems continuously learn from each patient.
We use advanced AI to decode high-resolution electrical signals and identify the unique fingerprint of each disease. These insights fuel personalized therapies that adapt in real time and provide clinicians with a new tool to understand and personalise treatment.

As we scale, we’re building the largest dataset of disease evolution and brain state in history, unlocking unprecedented insights into the brain and body.


Glioma management

SOMA-1 is our flagship device: a minimally invasive, MRI-safe brain–computer interface implanted during existing neurosurgery. SOMA-1 both monitors and treats brain disorders like gliomas in real time.

  • Closed-loop stimulation reduces disease burden as it evolves.
  • Continuous recording tracks tumor behavior without repeated scans.
  • Adaptive AI personalizes therapy based on live data from the tumor environment.



SOMA-1 is therapy, diagnostics, and a living model — all in a device the size of a shirt button.

A patient-first paradigm

Gone are the days of burdensome treatments — no more head shaving, messy gel applications, bulky headgear that overheats, or cumbersome equipment.

With Coherence, patients can maintain their appearances and focus on enjoying life. 



Patients are augmented by a holistic therapeutic system — a button-sized therapeutic implant; a modern, minimalist wearable that sits comfortably on top of the ear; and a user-friendly app. 

This system greatly enhances quality of life — allowing patients to live easier, healthier, longer, and more joyful lives.

Bioelectronic cancer management

By decoding the body's electrical language, we’re unlocking a new way to understand and treat disease.

  • Smarter: Personalized, real-time therapy for each patient.
  • Faster: Deployable across conditions without years of redevelopment.
  • Deeper: Reaching the core bioelectrical mechanisms of disease.


Coherence is laying the foundation of electro-oncology.
Welcome to a new paradigm in medicine.